Publications

Latest research publications at the Biological Cryo-EM facility

• Tubulin acetyltransferases access and modify the microtubule luminal K40 residue through anchors in taxane-binding pockets

• Testis-specific H2B.W1 disrupts nucleosome integrity by reducing DNA–histone interactions

• Structure and assembly of the α-carboxysome in the marine cyanobacterium Prochlorococcus

• Parental histone transfer caught at the replication fork

• Cryo-EM structure of TMEM63C suggests it functions as a monomer

• The Novel H2B Variant, H2BW2, Destabilizes Nucleosomes and Regulates Gene Expression During Early Human Spermatogenesis

 

• Cryo-EM structure of cyanophage P-SCSP1u offers insights into DNA gating and evolution of T7-like viruses

• Metallo-supramolecular branched polymer protects particles from air-water interface in single-particle cryo-electron microscopy

• Menin “reads” H3K79me2 mark in a nucleosomal context

• DDK promotes DNA replication initiation: Mechanistic and structural insights

• Structural insights into broadly neutralizing antibodies elicited by hybrid immunity against SARS-CoV-2

 

• Apicosome: newly identified cell-type-specific organelle in mouse cochlear and vestibular hair cells

• The human pre-replication complex is an open complex

• Abundant and cosmopolitan lineage of cyanopodoviruses lacking a DNA polymerase gene

• Biochemical and structural characterization of the cyanophage-encoded phosphate-binding protein: implications for enhanced phosphate uptake of infected cyanobacteria

• Application of metallo-supramolecular branched polymer improves particle distribution and orientation in single-particle cryo-EM

• Structural insights into broadly neutralizing antibodies elicited by hybrid immunity against SARS-CoV-2

• Cryo-EM structure of human hexameric MCM2-7 complex

• A broadly neutralizing antibody protects Syrian hamsters against SARS-CoV-2 Omicron challenge

• Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase